Prof. Dr. T-Y Dora Tang

University of Saarland, DE
Professor of Synthetic Biology

Supervisor DC4 and DC8

Professor of Synthetic Biology at the University of Saarland. PhD from Imperial College in membrane biophysics and then did a post-doc in the area of Origin of life and then in bottom up synthetic biology. Lab brings all of these elements together to address problems in the origin of life, modern biology and engineering. She has supervised and co-supervised 4 PhD students, currently supervising 3. Editor of ChemSysChem. Speaker of the Synthetic Biology work group for the German Society for Cell Biology (DGZ), advisory board for the European Synthetic Cell initiative. Awarded ERC consolidator grant in 2023. Authored and co-authored >40 publications.

Selected publications

  • Drobot, B., Iglesias-Artola, J. M., Le Vay, K., Mayr, V., Kar, M., Kreysing, M., … & Tang, T. D. (2018). Compartmentalised RNA catalysis in membrane-free coacervate protocells. Nature communications9(1), 3643. https://doi.org/10.1038/s41467-018-06072-w 
  • Ianeselli, A., Tetiker, D., Stein, J., Kühnlein, A., Mast, C. B., Braun, D., & Dora Tang, T. Y. (2022). Non-equilibrium conditions inside rock pores drive fission, maintenance and selection of coacervate protocells. Nature chemistry14(1), 32-39. https://doi.org/10.1038/s41557-021-00830-y 
  • Wollny, D., Vernot, B., Wang, J., Hondele, M., Safrastyan, A., Aron, F., … & Treutlein, B. (2022). Characterization of RNA content in individual phase-separated coacervate microdroplets. Nature communications13(1), 2626. https://doi.org/10.1038/s41467-022-30158-1 
  • Le Vay, K., Song, E. Y., Ghosh, B., Tang, T. Y. D., & Mutschler, H. (2021). Enhanced ribozyme‐catalyzed recombination and oligonucleotide assembly in peptide‐RNA condensates. Angewandte Chemie International Edition60(50), 26096-26104. https://doi.org/10.1002/anie.202109267 
  • Love, C., Steinkühler, J., Gonzales, D. T., Yandrapalli, N., Robinson, T., Dimova, R., & Tang, T. Y. D. (2020). Reversible pH‐responsive coacervate formation in lipid vesicles activates dormant enzymatic reactions. Angewandte Chemie132(15), 6006-6013. https://doi.org/10.1002/ange.201914893