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Xiuwen Lyu

University of Saarland (USAAR), DE

DC8: Evolution in heterogeneous populations of compartments

Supervisor: Prof. Dora Tang

Background

I started my academic journey in London in 2019. 3 years of undergraduate study in Imperial College London brought me into the world of Chemistry. In 2023, I continued with a master’s program at Imperial, focusing on methodology improvements and automating data analysis in solid-state nanopores.

Between my bachelor’s and master’s studies, I worked as an undergraduate researcher in Xiaoping Liao’s group at the Tianjin Bio-design Centre. Our project aimed to improve the yield of coumaric acid synthesis in Yarrowia lipolytica. This experience with complex metabolic networks and reaction pathways in model organisms made me want to find a more controllable life forms, leading me to explore artificial cells.

Luckily, my previous tutor James Hindley, a researcher specialised in CFPS artificial cell, agreed to teach me more about artificial cell though I’m not in his group during my master’s study. He also helped me when I was trying to find a PhD opportunity in artificial cells after I completed my master’s degree. During my search, Tang’s group caught my attention, not only for their work on artificial cell self-compartmentalisation but also for the goal of the whole group: to find the origin of life.

During my research in DarChemDN I wish to grab more techniques in artificial cell synthesis and apply my knowledge in data analysis to accelerate the building of high throughput synthesis-analysis pipeline of syntheticcoacervates.